Pre-Exposure Prophylaxis (PrEP) is an HIV prevention method that involves HIV-negative people taking anti-HIV medications daily to help prevent HIV infection. Several studies have shown that PrEP can reduce the risk of becoming HIV-infected when taken as part of a package of prevention services. In 2012, the US Food and Drug Administration approved the medication, Truvada, for the prevention of HIV infection in sexually active men and women. People using PrEP should be under the care of a medical provider and get regular HIV and STD testing.

In December 2013, San Francisco City Clinic completed enrollment for a PrEP demonstration project and is working on setting up an ongoing PrEP program at the clinic. Please refer to the City Clinic website for updates: City Clinic DOES offer post-exposure prophylaxis (PEP).

Where I can get PrEP?

  • San Francisco City Clinic has a PrEP coordinator who can provide information about current programs. For more information call 415.487.5578
  • Talk to your doctor about whether Truvada may be right for you.
  • Truvada for PrEP is covered by many private insurance plans and by Medical. California residents who do not have private insurance should contact Covered California for information on signing up for insurance or Medical. See the Covered California website for more info:


PrEP Fact Sheet: 

To find out the recommendations of the Health Department about PrEP for San Francisco residents read the PrEP Fact Sheet


For more information about PrEP:

PrEP Project Inform
My PrEP Experience
CDC PrEP Information

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