Completed Studies


The SEEDS study was a cross-sectional, behavioral study that used respondent-driven sampling (RDS) to recruit participants to learn more about patterns of alcohol use among men who have sex with men (MSM).


REBOOT is a pilot randomized trial to determine the feasibility and acceptability of a repeated-dose brief intervention to reduce overdose and risk behaviors among naloxone recipients.


NOSE was a nonrandomized intervention to determine the feasibility and acceptability of clinic-based naloxone co-prescribing to patients on chronic opioids among primary care providers in safety net clinics in San Francisco.


TREX was a controlled trail which enrolled participants who received naltrexone for extended release injectable suspension. The goal of this study was to see if this medication helps to reduce meth use.


NIP is a pilot study to evaluate the potential benefit of providing injectable naltrexone (XR-NTX) to a population of high-utilizers of medical services (HUMS) with alcohol use disorder.


ADIOS is a pilot project to develop, assess feasibility and evaluate an evidence-based academic detailing program to educate providers on naloxone prescribing within the context of an opioid safety agenda.

Project HOPE

Project HOPE is a multi-site, NIH-funded study within the NIDA Clinical Trials Network (CTN); San Francisco DPH led the clinical and intervention team for the trial, although the trial did not take place in San Francisco and the Principal Investigator was Dr Lisa Metsch. Project HOPE sought to address issues around HIV-infected persons who delay seeking care until their […]


LERNt was a study of brief education with naloxone distribution that found 5-10 minutes of education was sufficient for people who use opioids to recognize and respond to overdose events. Behar E, Santos GM, Wheeler E, Rowe C, Coffin PO. Brief overdose education is sufficient for naloxone distribution to opioid users. Drug Alcohol Depend. 2015 Mar 1;148:209-12.

Project ECHO

Project ECHO is a CDC-funded study to adapt and test the efficacy of Personalized Cognitive Counseling, a brief self-justification counseling intervention, on sexual risk and substance use among episodic substance-using HIV-negative men who have sex with men.

Showing 10 of 18 results