NOSE

The Naloxone for Opioid Safety Evaluation (NOSE) was a NIDA-funded R21 to implement and evaluate naloxone co-prescribing in 6 safety net primary care clinics in San Francisco. The study was a significant success, with multiple resulting publications.   1) Coffin PO, Behar E, Rowe C, Santos GM, Coffa D, Bald M, Vittinghoff E. Nonrandomized Intervention Study of Naloxone Coprescription for Primary …

Project MIX

Project MIX was a multi-site, six session behavioral intervention for substance using MSM. Men could be HIV-positive or negative, and more than half were African American or Latino. Participants were randomized to participate in the intervention sessions or video discussion groups, and were compared against a third group who received standard HIV testing and counseling. Project Mix showed that there …

BUMP

Methamphetamines are a major driver in the HIV epidemic. MSM who use meth are two to three times more likely to engage in risk behaviors that could lead to HIV. While medications exist to treat opiate, nicotine, and alcohol dependencies, currently there are no medications approved for methamphetamine addiction. The “BUMP” studies are designed to determine if medications can help …

COPING

COPING is a longitudinal cohort study of patients with chronic pain who use opioids, evaluating the impacts of opioids and evolving opioid prescribing practices on pain, function, and substance use parameters.

HIP: HIV Intervention for Providers

The purpose of this study was to encourage health care providers to evaluate high risk HIV transmission behaviors and offer prevention messages to their HIV-positive patients. It was hypothesized that patients of providers participating in the HIP intervention would report higher reduction in sexual risk practices than patients of the providers who were randomized into the control condition. Results after …